The Diagnostic Dilemma of Heyde Syndrome: A Case Report
Keywords:
Heyde, Dieulafoy Lesion, Cardiology, GastroenterologyAbstract
Heyde syndrome is a multisystem disorder characterized by the triad of aortic stenosis (AS), gastrointestinal bleeding, and acquired von Willebrand syndrome. We present the case of an 80 years old male that presented to us with a recurrent gastrointestinal bleed and syncope. Upon investigation it was found that the patient has clinically severe AS. On physical examination he had a grade 4/6 systolic murmur at the second right intercostal space radiating toward the right carotid artery. An upper GI endoscopy was planned which reported proximal jejunal AVM consistent with a Dieulafoy lesion. The history of lower gastrointestinal bleeding (angiodysplasia) and the presence of aortic stenosis were consistent with Heyde syndrome. Given the patient’s age and a high EuroSCORE, the patient was referred for transcatheter aortic valve implantation. The procedure was uneventful and the patient was discharged once stable. The patient did not experience gastrointestinal bleeding in the periprocedural period.
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